{"title":"Statistical analysis of the genotoxicity study results.","authors":"W Szymczak, B Przybojewska","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>One of the methods used in the genotoxicity study of chemical compounds is micronucleus test in vivo. There is no clear consensus as to which statistical method is most suitable to study the frequency of occurrence of micronucleated polychromatic erythrocytes. This paper proposes two statistical tests: approximate normal test and conditional binomial test (Kastenbaum & Bowman).</p>","PeriodicalId":77768,"journal":{"name":"Polish journal of occupational medicine","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polish journal of occupational medicine","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
One of the methods used in the genotoxicity study of chemical compounds is micronucleus test in vivo. There is no clear consensus as to which statistical method is most suitable to study the frequency of occurrence of micronucleated polychromatic erythrocytes. This paper proposes two statistical tests: approximate normal test and conditional binomial test (Kastenbaum & Bowman).