Club

Abstract

The Landmark feature is back and seeing as October is the month of Nobel prize announcements, it seems fitting to look back at some of the early Nobel prize-winning work on the ubiquitin-proteasome system. My last entry covered the 1975 discovery and purification of the protein UBIP/APF-1 (later to be known as ubiquitin) - and it was only a few years later that its links to proteolysis began to emerge