Modeling Thermoregulatory Responses to Cold Environments

Adam W. Potter, David P. Looney, Xiaojiang Xu, W. Santee, S. Srinivasan
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引用次数: 5

Abstract

The ability to model and simulate the rise and fall of core body temperature is of significant interest to a broad spectrum of organizations. These organiza-tions include the military, as well as both public and private health and medical groups. To effectively use cold models, it is useful to understand the first principles of heat transfer within a given environment as well as have an understanding of the underlying physiology, including the thermoregulatory responses to various conditions and activities. The combination of both rational or first principles and empirical approaches to modeling allow for the development of practical models that can predict and simulate core body temperature changes for a given individual and ultimately provide protection from injury or death. The ability to predict these maximal potentials within complex and extreme environments is difficult. The present work outlines biomedical modeling techniques to simulate and predict cold-related injuries, and discusses current and legacy models and methods.
模拟对寒冷环境的体温调节反应
对核心体温的上升和下降进行建模和模拟的能力对广泛的组织具有重要的意义。这些组织包括军队,以及公共和私人保健和医疗团体。为了有效地使用冷模型,了解给定环境中传热的基本原理以及了解潜在的生理学,包括对各种条件和活动的热调节反应是有用的。将理性原理或第一性原理与经验方法相结合,可以开发出实用的模型,预测和模拟特定个体的核心体温变化,并最终提供保护,使其免受伤害或死亡。在复杂和极端环境中预测这些最大电位的能力是困难的。目前的工作概述了生物医学建模技术来模拟和预测与寒冷相关的伤害,并讨论了当前和遗留的模型和方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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