Multi-modal Intermediate Fusion Model for diagnosis prediction

You Lu, Ke Niu, Xueping Peng, Jingni Zeng, Su Pei
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引用次数: 1

Abstract

The goal of the diagnostic prediction task is to predict what disease patients are likely to have at their next visit, based on their historical electronic medical records. Existing studies mainly conduct the prediction task by separately using discrete medical codes or clinical notes. However, few existing studies fuse multi-modal features from medical codes and clinical notes together for diagnostic prediction. Practically, using multiple modes of EHRs data can obtain more complete patient representation to improve the predictive performance of the model. Therefore, we proposed a Multi-modal intermediate Fusion Model (MFM) to predict patient diagnosis based on diagnostic codes and clinical notes. Specifically, MFM is mainly based on recurrent neural network to model data in different modes to extract effective features. Then, an intermediate fusion module is used to not only extract the global context information of data in each mode, but also capture the correlation between data in different modes. Finally, a multi-modal fusion matrix is generated for diagnosis prediction. Experimental results on a real dataset show that the proposed method improves the prediction performance compared with the baseline methods.
诊断预测的多模态中间融合模型
诊断预测任务的目标是根据患者的历史电子医疗记录,预测他们下次就诊时可能患什么疾病。现有的研究主要是分别使用离散的医学编码或临床笔记进行预测任务。然而,现有的研究很少将医学编码和临床记录的多模态特征融合在一起进行诊断预测。实际上,使用多种模式的电子病历数据可以获得更完整的患者表征,从而提高模型的预测性能。因此,我们提出了一个基于诊断代码和临床记录的多模态中间融合模型(MFM)来预测患者的诊断。具体来说,MFM主要是基于递归神经网络对不同模式下的数据进行建模,提取有效特征。然后,利用中间融合模块提取各模式下数据的全局上下文信息,同时捕捉不同模式下数据之间的相关性。最后,生成用于诊断预测的多模态融合矩阵。在真实数据集上的实验结果表明,与基线方法相比,该方法提高了预测性能。
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