[Perioperative antibiotic prophylaxis in allo-arthroplasty].

K Kluge, H Grasshoff, E M Weise, H Weickert
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Abstract

Since 1984 the perioperative prophylaxis was carried out using the antibiotics Oxacillin or Halospor in artificial joint replacement of the hip. We started with 1 g Oxacillin at the very beginning of the anaesthesie. Further 0.5 g Oxacillin were administered 2 and 6 hours later. 964 hip joints operated between 1982-1988 were followed up. We observed a marked decrease of the rate of infection from 7.2% to 1.0% after the introduction of the perioperative prophylaxis.

异体关节置换术围手术期抗生素预防。
自1984年以来,在人工髋关节置换术中进行围手术期预防使用抗生素Oxacillin或Halospor。我们在麻醉开始时用了1g氧苄西林。2小时和6小时后再给予0.5 g奥西林。在1982-1988年间对964例髋关节进行了随访。我们观察到围手术期预防措施引入后,感染率从7.2%显著下降到1.0%。
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