Clinico-Pathological Analysis of Osteomyelitis in Cancrum Oris (Noma) Patients Seen in Noma Children Hospital, Northwest Nigeria

B. Mujtaba, Chukwuma Benedict Chimezie, Aremu Ibikunle Adebayo, Abdurrazaq Taiwo, G. U. Ndubuizu, Abubakar Sadeeq Fawa
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引用次数: 3

Abstract

Background: Cancrum oris is a rapid and devastating infectious disease of the orofacial region, which can be life threatening in its fulminant stage. Infection of bone (osteomyelitis) is a possible sequelae of Noma (cancrum oris) and is more likely due to late presentation especially in our environment. A literature search revealed scanty research describing osteomyelitis in Noma patients. Objective: To analyze the clinico–pathology of osteomyelitis in Noma patients diagnosed and treated at Noma Children Hospital, Sokoto. Methods: The design was a 2-year retrospective study of records of Thirty–two patients who had sequestrectomy secondary to osteomyelitis in Noma (Cancrum oris). Age, gender, jaws affected and side of involvement were analyzed Results: The age ranged from 2–11 years with mean ±standard deviation 5.47 ± 2.68 years was recorded. Osteomyelitis in Noma patients was found among 17 (53.10%) males compared to 15 (46.90%) females. In 20 (62. 50%) of the cases, anterior maxillary involvement was observed and the remaining 12 (37. 50%) was found at the mandibular posterior region and it is more common on the left side. Result of histopathology showed both acute and chronic inflammatory cells. Necrosis and bone hyperactivity was observed in most of the slides. Conclusion: Osteomyelitis is a common complication of Noma and its treatment is of paramount importance for adequate management of Noma patients.  
尼日利亚西北部诺玛儿童医院口癌骨髓炎的临床病理分析
背景:口腔癌是一种快速和破坏性的口腔面部传染病,在其暴发性阶段可危及生命。骨感染(骨髓炎)可能是口癌(坏疽性口癌)的后遗症,更有可能是由于晚期出现,特别是在我们的环境中。文献检索显示,描述坏疽性口炎患者骨髓炎的研究很少。目的:分析索科托市诺玛儿童医院收治的坏疽性骨髓炎的临床病理特点。方法:该设计是一项为期2年的回顾性研究,对32例口癌骨髓炎继发骨髓炎的骨髓炎患者进行了骨髓炎切除手术。结果:年龄2 ~ 11岁,平均±标准差5.47±2.68岁。其中男性17例(53.10%),女性15例(46.90%)。1962年。50%的病例有上颌前受累,其余12例(37例)有上颌前受累。50%)见于下颌后区,多见于左侧。组织病理学检查显示有急性和慢性炎症细胞。多数载玻片可见坏死和骨质增生。结论:骨髓炎是坏疽性口炎的常见并发症,其治疗对坏疽性口炎患者的适当治疗至关重要。
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