Whole chromosome features of genomic signals

Abstract

The complex representation of the nucleotides derived from the projection of the Nucleotide Tetrahedron on an adequately oriented plane is used to convert sequences of nucleotides into complex digital genomic signals. This approach offers the possibility to use signal processing methods for the handling and analyzing of genomic information at the nucleotide, codon and amino acid levels in a multiresolutional approach. Some basic features of nucleotide sequences can be elicited using these signal representations. Specifically, the paper presents large scale features of eukaryote and prokaryote DNA genomic signals obtained with phase analysis methods that reveal regularities in the statistics of base distribution and of base-to-base transitions distribution along the DNA strands.