Visualization of Retinal Anatomical Structure Using Computer-Generated Holography

Rania M. Abdelazeem, Doaa Youssef, Salah Hassab-Elnaby, M. Agour
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引用次数: 2

Abstract

This study attempts to visualize the whole retina and its anatomical structures using only a single hologram giving the ophthalmologist an opportunity to examine it. Since all fundus cameras capture images for only a portion of the retina, retinal image registration was first applied to the captured images of the same eye to obtain a mosaic containing the complete map of the retina, allowing proper diagnosis. Then, accurate morphological detection of the main anatomical structures of the retina including blood vessels, macula and optic disc which are extremely important signs for estimating retinal disorders were extracted and/or highlighted on the mosaic. Subsequently, computer-generated holograms (GHs) of the mosaic, blood vessels, macula and optic disc were calculated using an adapted iterative approach based on the well-known Gerchberg-Saxton (GS) algorithm. The resulting CGHs were then holographically projected using a reflective phase-only spatial light modulator (SLM). In conclusion, the integration of CGH with fundus photography can be a valuable and crucial diagnostic tool for retinal disorders and can make significant contributions in the field of ophthalmology.
利用计算机生成全息技术可视化视网膜解剖结构
本研究试图可视化整个视网膜及其解剖结构,仅使用一个全息图给眼科医生一个检查它的机会。由于所有眼底相机只捕获视网膜的一部分图像,因此首先将视网膜图像配准应用于同一只眼睛的捕获图像,以获得包含视网膜完整地图的马赛克,从而进行正确的诊断。然后,提取和/或突出显示视网膜主要解剖结构的精确形态学检测,包括血管、黄斑和视盘,这是评估视网膜疾病的极其重要的标志。随后,使用基于著名的Gerchberg-Saxton (GS)算法的自适应迭代方法计算马赛克、血管、黄斑和视盘的计算机生成全息图(GHs)。然后使用反射纯相位空间光调制器(SLM)对所得的CGHs进行全息投影。综上所述,CGH与眼底摄影的结合是诊断视网膜疾病的一种重要而有价值的工具,可以在眼科领域做出重大贡献。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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