Study on Repeatability, Normalization and Feature Selection of Medical Electronic Nose for Lung Cancer Diagnosis

Shuya Zhang, Jing Luo, Mengchen Lu
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Abstract

In this paper, we report a medical electronic nose for lung cancer diagnosis used for breath analysis. We use the designed alveolar gas collector to collect the alveolar gas of subjects for the electronic nose experiment. The electronic nose system has completed chemical and exhaled breath tests. The results of chemical tests show the good repeatability of the developed medical electronic nose for lung cancer diagnosis in this paper, and the relative standard deviation (RSD) values of five feature classes are calculated, respectively. In the exhaled breath test, the test data are processed with six normalization methods. It is found that the data classification effect of the data after the quantile normalization is better than that after the other five normalizations. Then, the five feature classes are classified separately, and it is found that the feature class with low RSD value obtained from chemical tests has better classification effect, which provides a new way for feature selection.
医用电子鼻用于肺癌诊断的重复性、归一化及特征选择研究
本文报道一种用于肺癌诊断的医用电子鼻,用于呼吸分析。我们利用所设计的肺泡气体收集器收集被试的肺泡气体进行电子鼻实验。电子鼻系统已经完成了化学和呼气测试。化学试验结果表明,本文研制的医用电子鼻诊断肺癌具有良好的重复性,并分别计算了5个特征类的相对标准偏差(RSD)值。在呼气测试中,测试数据用六种归一化方法进行处理。发现分位数归一化后的数据分类效果优于其他五种归一化后的数据分类效果。然后分别对5个特征类进行分类,发现化学试验得到的RSD值较低的特征类分类效果较好,为特征选择提供了一种新的途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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