Adaptable chip-level microfluidic packaging for a micro-scale gas chromatograph

Abstract

In this paper, we present a robust and adaptable technique to integrate microfluidics with an on-chip thiolate-monolayer-protected gold nanoparticle coated chemiresistorarray for vapor analyte detection in a micro-scale gas chromatograph (μGC). The process involves mounting a sensing chip and capillary tubes within a silicon “extension carrier” (EC), capping the chemiresistor-array with a glass lid, and sealing the microfluidic package with non-sorbent epoxy. The stability and efficacy of the integrated detector cell is elucidated by consistent chip responses induced by the diffusion of vapor analytes though the detector cell.