Botox Injections for Spasticity and Sialorrhea

C. Mannix
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Abstract

In patients with cerebral palsy, injections of botulinum toxin type A (Botox) into muscle groups to reduce spasticity may decrease spasmodic pain and improve movement by increasing range of motion, thereby facilitating care and potentially lessening contracture development. This procedure requires little time but is painful, and repeated treatments are necessary. The level of sedation used for this procedure varies among institutions and from patient to patient, ranging from no sedation at all to general anesthesia. Minimal to moderate sedation with nitrous oxide is an effective method of sedation for this procedure. The sedationist must be prepared to handle complications such as emesis and aspiration. Injection of the submandibular and parotid glands for sialorrhea is a growing indication for Botox injection; deeper levels of sedation are required for sialorrhea than for spasticity to allow localization of the gland and precise delivery of the treatment.
注射肉毒杆菌治疗痉挛和唾液
在脑瘫患者中,向肌肉群注射A型肉毒毒素(Botox)以减轻痉挛,可能会减少痉挛性疼痛,并通过增加运动范围改善运动,从而促进护理并可能减少挛缩的发展。这个过程需要很少的时间,但很痛苦,并且需要反复治疗。在此过程中使用的镇静水平因机构和患者而异,从完全不镇静到全身麻醉。轻微至中度镇静氧化亚氮是一种有效的镇静方法。镇静医师必须准备好处理诸如呕吐和误吸等并发症。注射下颌骨和腮腺的唾液是一个日益增长的适应症,肉毒杆菌注射;与痉挛相比,唾液分泌需要更深层的镇静,以使腺体定位和精确的治疗。
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