[Genetic counseling in relation to drug intake in early pregnancy].

Arztliche Jugendkunde Pub Date : 1990-01-01
J Gedschold, R Becker, M Falk
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Abstract

In a series of 153 women with intake of drugs during early pregnancy the pregnancy was terminated in 22% of all cases. There were the following results of the 119 non-terminated pregnancies: delivery of a normal, healthy baby: 84%; abortion: 5%; still birth and premature birth, respectively: 3,5%. An abnormal phenotype was seen in 7% of the newborns, but only 3 cases with major malformation (cleft lip, club-foot, cataract) could be noted. Compared with normal pregnancies the results do not confirm an enhanced risk for malformations by intake of drugs during early pregnancy. Unfounded anxiety of physicians as well as of pregnant women with indicated pharmacotherapy should be reduced by better information and education.

[与妊娠早期药物摄入有关的遗传咨询]。
在153名怀孕早期服用药物的妇女中,22%的人终止了妊娠。119例未终止妊娠的结果如下:分娩正常、健康的婴儿:84%;堕胎:5%;死胎和早产分别占3.5%。新生儿表型异常占7%,但仅有3例出现重大畸形(唇裂、足畸形、白内障)。与正常妊娠相比,结果并不能证实妊娠早期服用药物会增加畸形的风险。应该通过更好的信息和教育来减少医生以及接受药物治疗的孕妇的毫无根据的焦虑。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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