V. Sánchez-Reyna, Sarella Belen Milla-León, Emilia Thayli Monzón-Ascensio, Juan Alberto Nima-Blas, Ronal Niquin-Huancajulca, A. Nolly-Loyaga, L. Otiniano-Ramos, M. Huamán-Rodríguez
{"title":"Diagnostic validity of mean platelet volume in neonatal sepsis: a systematic review","authors":"V. Sánchez-Reyna, Sarella Belen Milla-León, Emilia Thayli Monzón-Ascensio, Juan Alberto Nima-Blas, Ronal Niquin-Huancajulca, A. Nolly-Loyaga, L. Otiniano-Ramos, M. Huamán-Rodríguez","doi":"10.17268/rmt.2022.v17i4.5003","DOIUrl":null,"url":null,"abstract":"A systematic review study was carried out according to the standards of the PRISMA guide. We searched Medline, Pubmed, Central Cochrane and Embase databases. Observational studies (case-control and cohorts) that were published no more than 5 years ago and studied MPV as a diagnostic marker of NS, were included. From 60 articles identified, 12 were selected to be analyzed. We found that the diagnostic cut-off point for MPV ranged between 9.2 and 10.8 fL. In addition, the highest reported diagnostic sensitivity was 100%, and the lowest, 70%; while the specificity ranged from 33% to 94.4% according to each study. Conclusion: The MPV has a high sensitivity for the diagnosis of NS, however, the analyzed studies show a highly variable specificity.","PeriodicalId":150228,"journal":{"name":"Revista Médica de Trujillo","volume":"965 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Médica de Trujillo","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17268/rmt.2022.v17i4.5003","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A systematic review study was carried out according to the standards of the PRISMA guide. We searched Medline, Pubmed, Central Cochrane and Embase databases. Observational studies (case-control and cohorts) that were published no more than 5 years ago and studied MPV as a diagnostic marker of NS, were included. From 60 articles identified, 12 were selected to be analyzed. We found that the diagnostic cut-off point for MPV ranged between 9.2 and 10.8 fL. In addition, the highest reported diagnostic sensitivity was 100%, and the lowest, 70%; while the specificity ranged from 33% to 94.4% according to each study. Conclusion: The MPV has a high sensitivity for the diagnosis of NS, however, the analyzed studies show a highly variable specificity.
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