Efficacy Evaluation of DENTE91 Anti-Stain Toothpaste: Review of In-Vitro Studies

Harsh Shah, Ankita Singh
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Abstract

Background: Tooth stains on the front teeth are a common esthetic issue caused by tooth discoloration. Good oral hygiene habits, such as brushing your teeth twice daily with fluoride toothpaste and after meals, flossing daily, and using a whitening toothpaste, can help reduce staining and prevent cavities. Material & Methods: Many in-vitro studies has conducted to develop Dente91 Anti-Stain Toothpaste that can help in resolving the issue of demineralization, hypersensitivity, microbial strains, plaque, dental caries/tooth decay, and dental stain more effectively than other marketed products. Its composition includes ingredients such as Sodium Hexametaphosphate (SHMP), Polyvinylpyrrolidone (PVP), Tetrasodium Pyrophosphate, Covarine Blue, Zinc Citrate, Potassium Citrate, and Xylitol. Results: DENTE91 Anti-Stain toothpaste has over 99.9% significant antimicrobial efficacy and effectively reduces demineralization while enhancing the remineralization process. It also provides protection against acid attacks, promotes cell proliferation in NIH/3T3 cells, and shows significant healing activity on dental cavities. Additionally, it has the ability to occlude dentine disc lesions and reduce hypersensitivity. The findings of this study suggest that the toothpaste after using it twice a day for three days removes 63.02 % stains and also shows 80.33% improvement in teeth whitening from baseline.Conclusion: These in-vitro studies of dente91 anti-stain toothpaste concluded that toothpaste helps in resolving demineralization, hypersensitivity, plaque, dental caries/tooth decay, and dental stains. It has antimicrobial activity and teeth whitening effect too.
DENTE91抗污渍牙膏的体外研究综述
背景:门牙上的牙斑是牙齿变色引起的常见的审美问题。良好的口腔卫生习惯,例如每天用含氟牙膏和饭后刷牙两次,每天使用牙线,使用美白牙膏,可以帮助减少染色和预防蛀牙。材料与方法:许多体外研究已经进行,以开发Dente91抗污渍牙膏,可以帮助解决脱矿问题,过敏,微生物菌株,菌斑,龋齿/蛀牙,牙污渍比其他市场上的产品更有效。其成分包括六偏磷酸钠(SHMP)、聚乙烯吡罗烷酮(PVP)、焦磷酸四钠、科瓦林蓝、柠檬酸锌、柠檬酸钾和木糖醇。结果:DENTE91抗污牙膏抗菌效果显著,达到99.9%以上,有效减少脱矿,同时促进再矿化过程。它还提供防止酸攻击的保护,促进NIH/3T3细胞的细胞增殖,并显示出对蛀牙的显著愈合活性。此外,它具有闭塞牙本质盘病变和减少过敏的能力。本研究结果表明,每天使用两次,连续使用三天,可以去除63.02%的污渍,牙齿美白效果也比基线提高了80.33%。结论:这些dente91抗污渍牙膏的体外研究表明,牙膏有助于解决脱矿、过敏、牙菌斑、龋齿/蛀牙和牙渍。它还具有抗菌活性和牙齿美白作用。
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