Hydrogen peroxide, the effect on plaque and gingivitis when used in an oral irrigator.

Clinical preventive dentistry Pub Date : 1990-12-01
C M Jones, A S Blinkhorn, E White
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Abstract

The identification of plaque as the etiological agent in chronic gingivitis and the progression of chronic periodontitis, has intensified the search for effective chemical antiplaque agents to aid in the prevention and treatment of these diseases. To date, no ideal compound has been identified. Using the experimental gingivitis model, the effectiveness of a 1.5% hydrogen peroxide-containing oral rinse, applied as a conventional mouthrinse and in an oral irrigation device, was evaluated. The ability of the mouthrinse to inhibit the development of plaque and gingivitis in the two experimental groups, was compared with controls using a placebo rinse over two 7-day periods. At no time was there any statistical difference between either of the experimental groups and/or the placebo group in terms of gingival or plaque scores. This study concluded that a 1.5% hydrogen peroxide mouthwash was of no therapeutic value in the prevention or treatment of an experimental gingivitis, when used as a mouthrinse or in an oral irrigator.

过氧化氢,用于口腔冲洗器时对牙菌斑和牙龈炎的影响。
菌斑作为慢性牙龈炎和慢性牙周炎进展的病因的鉴定,加强了对有效的化学抗菌斑剂的研究,以帮助预防和治疗这些疾病。到目前为止,还没有找到理想的化合物。采用实验性牙龈炎模型,评估含1.5%过氧化氢漱口水作为常规漱口水和口腔冲洗装置的有效性。在两个实验组中,漱口水抑制菌斑和牙龈炎发展的能力与使用安慰剂漱口水的对照组进行了两个7天的比较。在任何时候,实验组和/或安慰剂组在牙龈或菌斑评分方面都没有任何统计学差异。本研究得出结论,1.5%过氧化氢漱口水在预防或治疗实验性牙龈炎方面没有治疗价值,当用作漱口水或口腔冲洗器时。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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