Indução de ovulação em pacientes com tumor estrogênio‐dependente: diretrizes clínicas da Sociedade Brasileira de Reprodução Humana

Reprodu??o & Climatério Pub Date : 2017-01-01 DOI:10.1016/j.recli.2016.02.001

Bruno Ramalho de Carvalho , João Pedro Junqueira Caetano , Mário Cavagna , Ricardo Mello Marinho , Adelino Amaral Silva , Hitomi Miura Nakagawa

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引用次数: 2

Abstract

Oncofertility is an interdisciplinary interest field of recent development, which aims to merge the knowledge in oncology and reproductive medicine, with the help of assisted reproductive technologies, to develop strategies for gonadal function preservation and to offer the possibility of biological procreation to cancer survivors. Preservation strategies of female fertility in oncological patients currently accepted for routine practice are the cryopreservation of embryos and cryopreservation of mature oocytes. It happens that ovulation induction is mandatory for executing both strategies, and with it the theoretical risk of stimulation of estrogen‐dependent tumors growth and the postponement of anti‐neoplastic treatment. Random‐start ovarian stimulation protocols include the intention of minimizing the delay in onset of chemo‐radiotherapy and to block tumor growth, providing satisfactory results, similar to those obtained in the usual beginning protocols. This article presents the clinical guidelines of the Brazilian Society of Human Reproduction for ovulation induction in patients with estrogen‐dependent tumors.

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雌激素依赖性肿瘤患者的排卵诱导:巴西人类生殖学会的临床指南

肿瘤生育是一个新兴的跨学科研究领域，它旨在将肿瘤学和生殖医学的知识结合起来，在辅助生殖技术的帮助下，制定性腺功能保存策略，并为癌症幸存者提供生物生殖的可能性。肿瘤患者女性生育能力的保存策略目前被接受的常规做法是胚胎冷冻保存和成熟卵母细胞冷冻保存。碰巧的是，排卵诱导是执行这两种策略的必要条件，同时也存在刺激雌激素依赖性肿瘤生长和延迟抗肿瘤治疗的理论风险。随机启动卵巢刺激方案包括最小化化疗-放疗开始的延迟和阻止肿瘤生长的意图，提供令人满意的结果，类似于通常的开始方案所获得的结果。这篇文章介绍了巴西人类生殖学会对雌激素依赖性肿瘤患者诱导排卵的临床指南。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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