A Framework for Codon Based Analysis to detect abnormalities responsible for Esophagus Cancer using Soft Computing Tool

Abstract

Deoxyribo Nucleic Acid (DNA) sequencing is a rapidly expanding biomedical research technology used for molecular diagnostics. It is basically a process of determining the precise order of nucleotide bases. The three unit nucleotide combinations within a DNA form codons which are related to amino acids and subsequently to proteins. One of the primary principles of disease detection is based on irregularities in the codon grouping. The focus of this work is to determine abnormalities in the codon sequence using soft computing tools and thereby provide a reliable computational mechanism for disease detection which have distinct genetic linkage.