The Detection of Seizure Vulnerable Period from Epidural EEG Recordings of Epilepsy Rat

Abstract

Detection of the seizure vulnerable period (SVP) is significant for epilepsy patients. Based on the construction of epilepsy rat model, we observed that SVP existed by long-term EEG recordings of a rat. Further analysis of the recordings by Lempel-Ziv complexity measure, we found that the complexities during the seizure vulnerable period were significantly lower than those during the seizure free period (SFP), which may help to predict and interrupt an imminent seizure