Microfluidic chip with world-to-chip interface for temperature detection in micro-nanoscale

N. Inomata, H. Maruyama, Takahiro Kato, F. Arai
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引用次数: 1

Abstract

In this paper, we proposed a microfluidic chip having a world-to-chip interface for multi-scale environmental measurement on a chip. There are several techniques for environmental measurement of the microscale objects using cantilever, microsensor and fluorescence method etc. Each technique has useful advantages against other methods. To employ these methods on a microfluidic chip simultaneously, we aim to develop a world-to-chip interface to insert a cantilever into the microfluidic chip and position it for sensing in a chip. We fabricated the microfluidic chip having this interface to insert the cantilever. This chip was designed to be used for inverted microscope. The solution does not leak from the interface by employing simultaneous flow control at both inlet and drain port. By using this interface, we demonstrated insertion and positioning of the cantilever into the microfluidic chip, and confirmed two-layer laminar flow control and detection of the local temperature change in the microchannel.
微流控芯片与世界芯片之间的接口,用于微纳米尺度的温度检测
本文提出了一种具有世界对芯片接口的微流控芯片,用于芯片上的多尺度环境测量。微尺度物体的环境测量技术有悬臂梁法、微传感器法和荧光法等。与其他方法相比,每种技术都具有有用的优势。为了在微流控芯片上同时应用这些方法,我们的目标是开发一个世界到芯片的接口,将悬臂插入微流控芯片并将其定位在芯片中进行传感。我们制作了具有该界面的微流控芯片来插入悬臂梁。该芯片是为倒置显微镜设计的。通过在进口和排放口同时进行流量控制,溶液不会从界面泄漏。通过该接口,我们演示了悬臂梁插入和定位到微流控芯片中,并验证了微通道中两层层流控制和局部温度变化的检测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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