Typing of specific monocyte antigens--another method for selection of bone marrow donors.

Abstract

In 10 patient-sibling pairs (sibling perspective bone marrow donor) the author typed HLA-A, B, DR and specific monocyte antigens MoP-1 to 6. Concurrent HLA-A, B and MoP identity was revealed in 80% of the cases, concurrent HLA-A, B, DR and MoP agreement in 60%. The author discusses the importance of this observation for the solution of the relationship between HLA and specific monocyte antigens. He recommends typing of specific monocyte antigens before transplantation of bone marrow as another way of donor selection.