MICROALBUMINURIA IS NOT ASSOCIATED WITH ENDOTHELIAL DYSFUNCTION IN OBESE AND OVERWEIGHT WOMEN, BUT IS STRONGLY CORRELATED WITH FASTING GLYCEMIA

Abstract

This study aimed to evaluate the association between endothelial dysfunction and microalbuminuria levels in overweight and obese women. Methods: This cross-sectional study analyzed secondary data of patients with BMI ≥ 25 Kg/m 2 who had microalbuminuria and endothelial function test already performed and inserted into the survey database. The endothelial function was evaluated by reactive hyperemia test (endothelium-dependent vasodilation). Results: This study included 41 women aged of 53 ­ ± 11 years, BMI of 32.56 ± 5.06 Kg/m 2 , WC  of 100.36 ± 23.21 cm. There was no correlation between microalbuminuria and endothelial function. A multivariate logistic regression analysis identified   glucose fasting (β = 0.804; p < 0,00,1) and HDL (β = - 0.309; p = 0.048) levels  as independent predictors of microalbuminuria. Conclusion: Microalbuminuria is not useful as a marker of subclinical atherosclerosis in this population, however can be associated to glucose fasting and HDL levels.