Food-dependent exercise-induced anaphylaxis without IgE sensitivity – a rare challenging condition

M. Geller
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引用次数: 0

Abstract

A 41 years-old healthy caucasian female, with a positive family history for atopy, refers that after eating crab and shrimp followed by aerobic exercises she develops severe generalized pruritus and diffuse urticaria, with large coalescent wheals. Emergency intravenous or oral antihistamines relieves her symptoms. She can eat shellfish without difficulties if not exercising afterwards. She also states that while exercising daily, there are no symptoms if she abstains from eating shellfish. Applying positive (histamine) and negative (diluent) controls, prick testing to shrimp, crab, oysters, scallops and clams were negative. She was advised to wait for 4 to 6 hours after having eaten shellfish to initiate aerobic exercises. An epinephrin autoinjector was supplied.
无IgE敏感性的食物依赖性运动引起的过敏反应-一种罕见的具有挑战性的条件
41岁健康白种女性,特应性家族史阳性,进食蟹、虾后进行有氧运动,出现严重全身性瘙痒和弥漫性荨麻疹,伴大细轮。紧急静脉注射或口服抗组胺药可缓解症状。如果之后不锻炼的话,她可以毫不费力地吃贝类。她还说,虽然每天锻炼,但如果她不吃贝类,就不会有任何症状。采用阳性(组胺)对照和阴性(稀释剂)对照,对虾、蟹、牡蛎、扇贝和蛤蜊进行点刺试验均为阴性。建议患者在食用贝类后等4至6小时再开始有氧运动。提供肾上腺素自动注射器。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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