Hyperfiltration in Diabetic Patients Associated With Mild Hyponatremia

Abstract

Glomerular hyperfiltration found in diabetic patients is recognized as an early renal alteration and reversible stage of kidney damage, but details have not yet been studied. We investigated the relation among estimated glomerular filtration rate (eGFR) and many factors such as age, HbA1cvalue, blood urea nitrogen (BUN) concentration, Na and K concentrations in serum of Japanese diabetic patients to investigate the characteristics of hyperfiltration [1]. Hyperfiltration (eGFR ≥ 120 ml/ mini/1.73 m 2 ) was found in six among 60 diabetic patients investigated, and Na concentrations in five patients with hyperfiltration were slightly