Decreasing the gap between emerging nanotechnologies and citizen through ethical considerations and socially responsible research: the example of nano-drugs

J. André, C. Frochot, R. Manigat, F. Allix, F. Tomei
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Abstract

Decisions about the use of science are "existential" to the extent that they concern human well-being, that is, how people think, develop, act -- how they live. Scientists working within their own disciplines tend to depend on paradigms and these usually entail mandatory sets of rigid norms. These permit serious and deep pursuit of knowledge but by themselves don't respond to, let alone overcome, gaps that open between scientific research itself and demands or needs for public determination of the social applications of research. Researchers must often cope with heavy time pressures for the financing and the publication of their work. This tends to minimize interdisciplinary efforts and confirm the priorities of decision-makers who provide financing. The matter is complicated by increasing demands from the public that scientists factor into their efforts important ethical questions concerning social, economic and political matters. This makes the requisite tools interdisciplinary and there is a general absence of agreed-on rules for their development and use. Recent fascination with nanotechnologies as keys to scientific progress suggests the possibility of crafting appropriate priorities that are not always dependent on calculations of profit. A variety of risks -- ethical, health, environmental -- arise at the beginning of a project and they bring complexity and interdependence throughout the effort. Again: these entail social and not solely scientific issues and they cannot be glossed over. This paper aims to press scientists to consider and reflect on the possible future uses of their accomplishments (in terms of ethics and risks or hazards for Humans and the environment). It proposes certain humbleness on their part together with a principle of "Socially Responsible Research" when, for example, applying new nano-drugs in cancer therapy (including limits of perception of possible problems of researchers and few modest action proposals for a social progress).
通过伦理考虑和对社会负责的研究缩小新兴纳米技术和公民之间的差距:纳米药物的例子
关于科学应用的决定在某种程度上是“存在的”,因为它们关系到人类的福祉,即人们如何思考、发展、行动——他们如何生活。在自己的学科内工作的科学家往往依赖于范式,而这些范式通常需要强制性的严格规范。它们允许对知识进行认真而深入的追求,但它们本身并没有回应,更不用说克服科学研究本身与公众决定研究的社会应用的要求或需要之间的差距了。研究人员必须经常应付资助和发表其工作的沉重时间压力。这往往会减少跨学科的努力,并确认提供资金的决策者的优先级。公众越来越多地要求科学家在他们的工作中考虑到有关社会、经济和政治问题的重要伦理问题,这使问题变得复杂。这使得必要的工具是跨学科的,并且普遍缺乏商定的开发和使用规则。最近人们对纳米技术的痴迷,认为它是科学进步的关键,这表明有可能制定出不总是依赖于利润计算的适当优先级。各种各样的风险——伦理的、健康的、环境的——在项目开始时就出现了,它们在整个努力过程中带来了复杂性和相互依赖性。再次强调,这些问题不仅涉及科学问题,还涉及社会问题,不能被掩盖。这篇论文的目的是促使科学家们考虑和反思他们的成就在未来的可能用途(在伦理和对人类和环境的风险或危害方面)。例如,在将新的纳米药物应用于癌症治疗时(包括限制研究人员对可能出现的问题的认识,以及为社会进步提出的一些适度的行动建议),它建议他们在一定程度上保持谦逊,同时提出“对社会负责的研究”原则。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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