Pedestaled subwavelength grating metamaterial waveguide for sensitivity enhancement (Conference Presentation)

Ching-Wen Chang, Xiaochuan Xu, S. Chakravarty, Hui-Chun Huang, Q. Y. Chen, L. Tu, Ray T. Chen
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Abstract

Silicon photonics has been studied intensively for biosensing applications due to the potential of leveraging the matured fabrication process to integrate thousands of sensors on a single chip and massively produce sensing chips at an affordable cost. However, the high index contrast of silicon does not only enable ultra-compact sensors, but also limits the interaction between optical field and analytes. To enhance the sensitivity, silicon subwavelength grating metamaterial (SGM) microring resonator was proposed to improve the interaction between photons and analytes and has demonstrated significant sensitivity improvement. Due to the asymmetric index profile along the vertical direction, further increasing the sensitivity becomes challenging. To reduce the asymmetricity, in this paper, we propose pedestaled SGM which allows further increasing the interaction between optical field and analytes. We analyzed and demonstrated enhanced bulk sensitivity and limit of detection (LOD) in SGM microring resonators with pedestal structure. To compare the bulk sensitivity and LOD of regular SGM microring resonator (Sample A) and pedestal SGM microring resonators, the devices with same structure design as Sample A were soaked in buffered oxide etch (BOE) for 30 seconds (Sample B) and 50 seconds (Sample C) to make pedestal shape. Real time monitoring of the resonance shift measurement shows the detection of streptavidin at a low concentration of 0.1 ng/mL for Sample C and a similar response for 1 ng/mL, 10 ng/mL, 100 ng/mL, 1 μg/mL, 10 μg/mL, and 100 μg/mL. Our results suggest that such pedestaled SGM microring resonators have great potential for specific biomarkers diagnosis.
用于灵敏度增强的基座亚波长光栅超材料波导(会议报告)
由于利用成熟的制造工艺将数千个传感器集成在单个芯片上并以可承受的成本大规模生产传感芯片的潜力,硅光子学已被广泛研究用于生物传感应用。然而,硅的高折射率对比度不仅使超紧凑传感器成为可能,而且还限制了光场与分析物之间的相互作用。为了提高灵敏度,提出了硅亚波长光栅超材料(SGM)微环谐振腔来改善光子与分析物之间的相互作用,并证明了灵敏度的显著提高。由于垂直方向上的折射率分布不对称,进一步提高灵敏度变得具有挑战性。为了减少不对称性,本文提出了一种可进一步增加光场与分析物相互作用的基座式SGM。我们分析并证明了具有基座结构的SGM微环谐振器提高了整体灵敏度和检测限(LOD)。为了比较常规SGM微环谐振器(样品A)和基座式SGM微环谐振器的体灵敏度和LOD,将与样品A结构设计相同的器件在缓冲氧化物蚀刻(BOE)中浸泡30秒(样品B)和50秒(样品C)以形成基座形状。实时监测的共振位移测量显示,样品C在低浓度(0.1 ng/mL)下检测到链霉亲和素,在1 ng/mL、10 ng/mL、100 ng/mL、1 μg/mL、10 μg/mL和100 μg/mL下检测到相似的响应。我们的研究结果表明,这种基座式SGM微环谐振器在特定生物标志物诊断方面具有很大的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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