Retirement and Management of Diabetes in Medically Under-served Patients with Type 2 Diabetes: Preliminary Findings and Literature Review

I. Obasanjo, W. Mann
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Abstract

Background: Studies have found that diagnosis of Type 2 diabetes increases the risk of early retirement in the high-income countries. In this study, we examined the levels of glycated hemoglobin (HbA1c) by employment status to determine if early retirement confers a benefit to managing diabetes. Methods: The data was from a primary care center serving the uninsured and medically underserved in the greater Williamsburg area in the State of Virginia. Plasma concentration of HbA1c (%) from the last visit was used to measure the average level of blood glucose and as an assessment test for glycemic control in people with diabetes. Data analyses were carried out using general linear regression with HbA1c as the dependent variable and employment status, gender and age as the independent variables; and the interaction of gender and employment status and interaction of age and employment status were assessed to control for potential confounding factors. Results: The results showed that males tended to have a higher level of HbA1c; overall age was negatively associated with the levels of HbA1c; there was a significant difference in the mean levels of HbA1c between the retired people and people working part-time (p=0.032). After controlling for age and gender in the multiple linear regression analysis, employment status became non-significantly associated with HbA1c levels. Post hoc analysis showed a difference in HbA1c between individuals working part-time (the highest HbA1c group) and the full-time employed at a marginal significance (p=0.0823). While almost 20 years older, the retired people had the lowest level of HbA1c. However, the mean level of HbA1c was no longer significantly different from that in other groups, probably because age explained much of this variation in the levels of HbA1c among employment status. Multiple regression analysis showed that age was negatively associated with the levels of HbA1c (The retired people mainly derived Beta=-0.046, p<0.0001). Conclusion: In this underserved population, the HbA1c level is the lowest in people after retirement, even though they are older. Our study indicates that retirement may be a beneficial factor for the management of diabetes, which warrants further investigation.
医疗服务不足的2型糖尿病患者的糖尿病退休和管理:初步发现和文献综述
背景:研究发现,在高收入国家,2型糖尿病的诊断增加了提前退休的风险。在这项研究中,我们通过工作状态检查了糖化血红蛋白(HbA1c)水平,以确定提前退休是否有利于控制糖尿病。方法:数据来自一个初级保健中心,服务于弗吉尼亚州大威廉斯堡地区的无保险和医疗服务不足的人群。最后一次就诊时的血浆HbA1c浓度(%)用于测量平均血糖水平,并作为糖尿病患者血糖控制的评估试验。数据分析采用一般线性回归,以糖化血红蛋白为因变量,就业状况、性别、年龄为自变量;评估性别与就业状况的相互作用以及年龄与就业状况的相互作用,以控制潜在的混杂因素。结果:男性患者HbA1c水平较高;总体年龄与HbA1c水平呈负相关;退休人员和兼职人员的平均HbA1c水平差异有统计学意义(p=0.032)。在多元线性回归分析中控制了年龄和性别后,就业状况与HbA1c水平无显著相关性。事后分析显示,兼职人员(HbA1c最高组)和全职人员的HbA1c差异具有边际显著性(p=0.0823)。虽然年龄大了近20岁,但退休人员的糖化血红蛋白水平最低。然而,HbA1c的平均水平不再与其他组有显著差异,这可能是因为年龄在很大程度上解释了不同就业状态下HbA1c水平的差异。多元回归分析显示,年龄与HbA1c水平呈负相关(以退休人群为主推导Beta=-0.046, p<0.0001)。结论:在这些服务不足的人群中,退休后的HbA1c水平最低,即使他们年龄较大。我们的研究表明,退休可能是糖尿病管理的一个有益因素,值得进一步研究。
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