Usage areas of nanoparticles in veterinary dermatology

Abstract

Elements such as gold and silver have been used to treat various diseases since ancient times. These elements, which are used today, have been diversified and sized with many researches. Recently, it is seen that nanoparticles are frequently used in the medical field. Nanoparticles can be 1-1000 nanometers in size and gain biological, physical and chemical functionality due to their nano size. The type and size of these nanoparticles are chosen according to the area in which they will be used. These prepared drugs are used for purposes such as biosensor imaging, transporting drugs to the target organ, protecting the transported substance against denaturations, increasing the immunological response, and transporting chemotherapeutic drugs. Today, with the increase in the number of dermatological cases in clinics, different treatment methods and systems are being developed. There are various nanoparticles used in dermatological cases to increase the bioavailability of topical, oral or injectable drugs and to increase the effect in the targeted area. These drugs have been used in conditions such as antimicrobial, antiparasitic, antifungal, allergen-specific immunotherapy, wound healing, tumors and atopic dermatitis. Many studies have also been carried out in the field of dermatology and it has been shown that nanoparticles used for follicular application provide advantages in dermal drug delivery, including improved skin bioavailability, increased depth of penetration, prolonged residence time, rapid transport to the skin and tissue targeting, in dermal drug delivery by using the appropriate nanoparticles in the right sizes. Particles can collect in the follicular opening and penetrate through the follicular canal when applied to the skin surface. This review has been prepared to investigate the usability of nanoparticle-derived drugs used in human medicine in veterinary applications.