Cytogenetics of endometrial adenocarcinoma.

Abstract

The results of karyotypic analysis of a new case of endometrial adenocarcinoma revealed in all analyzed diploid or near-diploid cells two chromosomes 1 of normal morphology and the presence of a marker or markers derived from chromosome 1. No other common chromosome marker was observed. Among a total of 25 endometrial adenocarcinoma cases reported in literature, including the case we reported, the most frequent chromosome abnormality-observed was trisomy and tetrasomy of the long arm of chromosome 1 which may represent a specific karyotypic change in at least one subtype of this tumor.