Evaluation of Clinical Efficacy of Cissus quadrangularis in Pain Management and Bone Healing after Implant Placement: A Pilot Study

Abstract

Background: The ancient ayurveda science of medicine describe s various herbal preparations that achieve the hastening of bone healing and reli eve from pain and swelling. Aim: To evaluate the clinical efficacy of cissus quadrangularis in p ain management and bone healing after implant placement. Objectives: To evaluate the clinical and bio chemical parameter s using cissus quadrangularis after implant placement in terms of measurements of pain, swelling, serum alkaline phosphatase level and bone density around implant. Type of Study: Prospective Randomized Control Study. Materials and Methods: Patients were divided in two groups. Study group and Control group. Three patients in ea ch group received implants either single implants or multiple implants. Study group was give n cissus quadrangularis without any additional medicine and control group was given rou tine antibiotics (Amoxicillin 500mg and diclofenac sodium). Pain was assessed using VAS at 3, 5 day and after one week, swelling was checked in form of mild, moderate and severe, a nd serum alkaline phosphatase was recorded pre-operatively and 4 th and 8 week of post-operative to evaluate bone healing. P atents’ Orthopantomogram were subjected to densitometric an alysis for evaluating the changes in the bone density in both the study and control group. Results: Pain and swelling were minimal and bone healing was more in study group and less in co ntrol group. There was an increase in serum alkaline phosphatase level at different follow ups in study groups when compared to control group. Densitometric analysis showed significant im provement in bone density around implant in study group when compared to control group. Conclusion: Use of cissus quadrangularis after implant placement showed significant effect on pain and swelling management. Also rising level of serum alkaline phosphatase and good bone density when compared to control group indicated new bone formation thus helps in osteointegration.