Scaled FitzHugh-Nagumo equations as building blocks for modelling dynamics adjusted to measurable biophysical data

Abstract

We apply the method of scaling fitting of the FitzHugh-Nagumo equation to describe a circuit consisting of the two coupled neurons aimed to reproduce non-stationary EEG modulations of theta-rhythm emerging during a rat's run along a linear track. It is shown that such an approach allows a quantitative reproduction of recorded oscillations and, therefore, may be used for a further development of computational models describing the spatial navigation in a rat brain.