Lensfree Microfluidic On-chip Flowing Cell Imaging with Integrated Surface Acoustic Wave Pumping

Abstract

One lensfree microfluidic on-chip flowing cell imaging system with integrated SAW pumping is proposed in this article. The SAW device temperature responses are characterized to be below 40 °C so as not to harm cells. Different resolution enhancing techniques are implemented and compared. It is demonstrated that machine learning based methods exceed those interpolation based ones, and a training library of individual cell type helps improve the SSIM compared with a training library of combined cell types.