Development of 3D computational models of biodegradable meshes

Abstract

The number of pelvic organ prolapse (POP) cases has been increasing over the years, affecting the lives of countless people around the world. To try to solve this problem, synthetic meshes were introduced until the FDA banned the commercialization of some of these meshes, and therefore new approaches are urgently needed [1]. Thus, the possibility of developing biodegradable meshes arises to overcome the problems encountered so far with the use of synthetic meshes, mainly due to their biocompatibility and biomechanical properties. Besides its main functionality of guaranteeing organ support, it presents good characteristics regarding its flexibility and resistance, thus guaranteeing a better reinforcement of the intervened region, avoiding eventual tissue injuries. This abstract focuses on the development of computational models of biodegradable meshes that, in the future, can be used to treat the POP.