Relación entre la viscosidad sanguínea y la perfusión tisular

Abstract

Background: Hemorrhagic shock is one of the leading causes of death in the surgical and polytraumatized patient. The central goal: Of every reanimation maneuvers is to bring oxygen to the cells, requiring an adequate management of macro and micro hemodynamic variables. The blood viscosity, one of these variables, plays a very important role. Methods: An experimental study was carried out with 10 pigs which were randomly divided in two groups. Both groups were exanguinated to a 70% of their blood volume. In the first group, named Group H, the fluid reposition was made with HES, while in the second group, named Group S, was made with autologous blood. Hourly assessment of macro and micro hemodynamic variables, and plasmatic viscosity, was carried out for six hours. Results: The results obtained were individually analyzed. Lactate, central venous oxygen saturation and bases exces values were taken to measure tissue perfusion. These values were reflected in tables and figures, and were analyzed together with the viscosity of the swine blood. Conclusions: On the basis of the results of ours measurements we can infer that the tissue perfusion was better when the maintenance of plasmatic and, secondarily, blood viscosity values were prioritize over the hematocrit level. However more studies are needed to confirm this theory.