A 57-year-old alcoholic woman with soft neck mass

L. Miranda, A. C. Miranda, Matheus Stillner Eufrânio, Maria Vitória Rocha Santos Bezerra Maia
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Abstract

A 57-year-old woman was diagnosed with an anterior cervical mass (figure 1). No peripheral neuropathy or cervical lymph nodes were detected from the physical examination. The mass has slowly and painlessly grown for 30 years with no dyspnea or dysphagia. She had a history of chronic alcohol consumption and heavy tobacco use for 25 years. No standard medications were taken. Multiple symmetric lipomatosis is a disease characterized by the accumulation of multiple, benign, symmetric, and nonencapsulated fatty tissue masses. This is more common in males (15:1) and in the Mediterranean population. Malignancy is rarely observed in this case. Masses can be found on the head and neck, including the upper trunk, shoulders, upper back, mediastinum, perineum, scrotum, and tongue. Besides the aesthetic effects, masses can cause airways or digestive compressive symptoms, as well as limitations in head or neck movements, urinating, or sexual intercourse. The involvement of peripheral nerves can cause neurological symptoms.   Alcohol abuse has been long associated with this disease.  A genetic cause has been suggested, but a hereditary pattern has not been identified in most cases. A link was suggested with liver disease, but there is no mention of liver abscess in the literature.   The diagnostic is based on image finds. Solitary lipoma is a benign soft tissue tumor, rarely found in the neck region. It mostly occurs in females and obese patients, and it is enclosed by a fibrous capsule that helps to differentiate it from other fat aggregations. Liposarcoma represents 1% of neck and head sarcomas. Patients are mostly men and the medium age is 70 years. Familial multiple lipomatosis is a rare autosomal dominant disease that is manifested in the thirties and is more prevalent in females (2:1). In this case, the discrete multiple subcutaneous nodules are movable, painless, and soft and have no associated conditions.   Lipectomy is the concerned treatment, but recurrence is common. Liposuction is an alternative to extensive lipectomy. No medicinal therapy is effective; however, alcohol abstinence can reduce the recurrence frequency.   Clinics must be aware of this uncommon disease in order to diagnose it and treat it appropriately.   Statement of Ethics Written informed consent was obtained from the patient for publication of this case report and any accompanying images.   Conflict of Interest Statement The authors have no conflicts of interest to declare.   Funding Sources The authors had no funding sources in the preparation of data or the manuscript.
一名57岁的酗酒女性颈部软质肿块
一名57岁女性被诊断为颈椎前路肿块(图1)。体格检查未发现周围神经病变或颈部淋巴结。肿块缓慢无痛生长30年,无呼吸困难或吞咽困难。她有25年的长期饮酒和重度吸烟史。没有服用标准药物。多发对称型脂肪瘤病是一种以多发、良性、对称、非包裹性脂肪组织肿块堆积为特征的疾病。这在男性和地中海人群中更为常见(15:1)。在本病例中很少观察到恶性肿瘤。肿块可见于头颈部,包括上躯干、肩部、上背部、纵隔、会阴、阴囊和舌头。除了美观外,肿块还可引起气道或消化道受压症状,以及头颈部运动、排尿或性交受限。累及周围神经可引起神经系统症状。长期以来,酗酒一直与这种疾病有关。已经提出了遗传原因,但在大多数情况下尚未确定遗传模式。这与肝脏疾病有关,但文献中没有提到肝脓肿。诊断是基于图像发现。孤立性脂肪瘤是一种良性软组织肿瘤,很少发现于颈部。它主要发生在女性和肥胖患者中,它被纤维囊包围,有助于将其与其他脂肪聚集区分开。脂肪肉瘤占头颈部肉瘤的1%。患者多为男性,中位年龄70岁。家族性多发性脂肪瘤病是一种罕见的常染色体显性遗传病,多见于30多岁的女性(2:1)。在这种情况下,离散的多个皮下结节是可移动的,无痛的,柔软的,没有相关的条件。除脂术是常用的治疗方法,但复发是常见的。抽脂是广泛的脂肪切除术的替代方法。药物治疗无效;然而,戒酒可以减少复发频率。诊所必须意识到这种罕见的疾病,以便诊断和适当治疗它。本病例报告和任何随附图片的发表均已获得患者的书面知情同意。利益冲突声明作者无利益冲突需要声明。作者在准备数据或稿件时没有资金来源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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