Guidelines and reality in studies on the economic costs of alcohol use: a systematic review

Sinclair Carr, J. Rehm, J. Manthey
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引用次数: 5

Abstract

Aim: To identify guidelines for estimating alcohol-attributable cost of illness (COI) and actual COI studies, and to assess to what extent core recommendations have been implemented. Design: The systematic review was conducted in February 2019 according to the PRISMA statement. Relevant COI guidelines and actual alcohol COI studies published since 2009 (when the last systematic review was published) were identified by searching databases MEDLINE and EMBASE, as well as literature known by the authors. Measures: Standards and recommendations of published COI guidelines, and actual COI studies estimating the total costs of alcohol. Findings: Fourteen guidelines and eighteen COI studies were identified, and relevant indicators were extracted. Large discrepancies between recommended and implemented methods were determined. Contrary to most current guidelines, which were barely acknowledged at all, (a) predefined direct and indirect cost groups were only partially included, (b) estimates were compared with GDP in only about half of the studies, and (c) avoidable costs – a complementary concept to the more common scenario of complete alcohol abstinence – were never estimated. Conclusions: Adherence to guidelines in published COI studies is low. We propose content-related and software-based solutions to adopting a common standard, which could reduce heterogeneity and enhance comparability in alcohol COI studies.
关于酒精使用经济成本研究的指导方针和现实:系统回顾
目的:确定估计酒精归因疾病成本(COI)和实际COI研究的指南,并评估核心建议的实施程度。设计:根据PRISMA声明,系统评审于2019年2月进行。通过检索数据库MEDLINE和EMBASE以及作者已知的文献,确定了自2009年(最后一次系统评价发表时)以来发表的相关COI指南和实际酒精COI研究。措施:公布的COI指南的标准和建议,以及估计酒精总成本的实际COI研究。结果:确定了14项指南和18项COI研究,并提取了相关指标。确定了推荐方法和实施方法之间的巨大差异。与大多数几乎不被承认的现行指导方针相反,(a)只部分地包括了预先确定的直接和间接成本组,(b)只有大约一半的研究将估计数与国内生产总值进行了比较,(c)可避免的成本——对更常见的完全戒酒情况的补充概念——从未进行过估计。结论:在已发表的COI研究中,对指南的依从性较低。我们提出了与内容相关和基于软件的解决方案,以采用共同标准,这可以减少酒精COI研究的异质性并增强可比性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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