[Alcohol withdrawal syndrome in the postoperative phase--therapy or prevention?].

T Heil, D Martens, K Eyrich
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Abstract

In a prospective study 50 patients who reported regular ethanol consumption and who underwent neck dissection were evaluated by clinical examination and the Munich alcohol test (MALT). 31 patients were not classified as alcohol abusers and none of them developed withdrawal symptoms (WS) postoperatively. 19 patients were diagnosed as alcohol abusers; 9 of them (group 1) received symptomatic therapy with clomethiazol and haloperidol, 10 patients (group 2) received continuous ethanol infusions (2-4 g/h) postoperatively as prophylaxis for WS. 6 patients in group 1 developed WS; none of group 2 developed WS. Thus the period of intensive care therapy of group 2 was significantly shorter (3.0 versus 11.5 days). It was concluded that postoperative continuous ethanol infusions prevent the occurrence of WS and should be administered to severely alcoholic patients.

[术后酒精戒断综合征——治疗还是预防?]
在一项前瞻性研究中,通过临床检查和慕尼黑酒精试验(MALT)对50例定期饮酒并接受颈部解剖的患者进行了评估。31例患者未被归类为酒精滥用者,术后均未出现戒断症状(WS)。19例患者被诊断为酒精滥用;其中9例(1组)采用氯美唑联合氟哌啶醇对症治疗,10例(2组)术后连续输注乙醇(2 ~ 4 g/h)预防WS。1组6例发生WS;2组无WS发生。因此,2组的重症监护治疗时间明显缩短(3.0天比11.5天)。结论:术后持续乙醇输注可预防WS的发生,对重度酒精中毒患者应给予乙醇输注。
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