Thermodynamics of complexation and membrane activity of crown ethers

Abstract

The use of thermodynamic characteristics in the analysis of data on complexation makes it possible to give the obtained data a definite physical and chemical interpretation. Our studies allow us to evaluate the complex forming abilities of compounds similar in structure to the molecules studied, and will help to analyze the "structure-function". They can replenish the database on the physical and chemical properties of crown ethers, and enable the prediction of only "constructed compounds". We have developed a reliable set of procedures for conductometric analysis of complex forming, membrane active and thermodynamic properties of sulfo derivatives-DB18C6, diacyl derivatives-DB18C6, 4’,4"(5")-dimethylaminoethanolDB18C6 and bis-o-methoxyphenoxy-diethyl ethers.