[Acute changes of coronary and global hemodynamics in patients with angina pectoris and arterial hypertension caused by celiprolol and metoprolol].

Radiologia diagnostica Pub Date : 1990-01-01
N Franz, D Modersohn, G Linss, B Heublein, G Gola, L Bruch, T Walde
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引用次数: 0

Abstract

In 30 hypertensives with angina pectoris the acute action of beta-blockers Celiprolol and Metoprolol on the global and coronary haemodynamics was tested within cardiac catheter diagnostics. In accordance with no long-term effects Metoprolol acts negatively inotrope, chronotrope as well as pre- and post-load increasing. Celiprolol lowered the pre- and postload, and increased the cardiac output, but did not influence the heart rate. Both medicaments increased coronary flow and myocardiac oxygen consumption. From the mentioned effects important conclusions for therapy with both Beta-blockers can be derived.

[塞利洛尔和美托洛尔致心绞痛和动脉高血压患者冠状动脉和全身血流动力学的急性变化]。
在30例合并心绞痛的高血压患者中,在心导管诊断中检测了-受体阻滞剂塞利洛尔和美托洛尔对全身和冠状动脉血流动力学的急性作用。根据无长期效应,美托洛尔负性地作用于肌力、时变性以及负荷前后增加。塞利洛尔降低负荷前和负荷后,增加心输出量,但不影响心率。两种药物均增加冠状动脉血流和心肌耗氧量。从上述效果可以得出两种受体阻滞剂治疗的重要结论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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