A Comparative Study to Assess the Quality of Bone following Ridge Augmentation with Autografts and Allografts: A Prospective Study

Arjun Krishnadas, R. Subramanian, G. Giri
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Abstract

Aim: The aim of this study was to investigate the quality of bone at the augmented site in the anterior maxilla and mandible. Materials and methods: Ten patients with inadequate bone for implant placement were included in this study. Of these 10 patients with inadequate bone volume, five were chosen to be treated with autogenous bone grafts (AT) and rest five patients were treated with freeze dried corticocancellous allografts (AL). Three months following grafting, biopsies of the grafted area were obtained using a 3 mm trephine bur and were histologically evaluated. Results: Histological analysis revealed areas of new bone formation with thick trabeculae with lacunae containing osteo­ cytes in the autogenous group, whereas the allograft group showed segments of necrotic bone with empty lacunae. Although, the AL group has an inherent advantage of avoidance of a secondary surgical site, showed decreased bone remodeling as compared to the autografts. Conclusion: All the 10 patients underwent implant placement. The reports regarding the nature of bone obtained during implant placement clearly depicts a comparable histological variation at the grafted site.
评估自体骨和同种异体骨嵴增强后骨质量的比较研究:一项前瞻性研究
目的:本研究的目的是研究上颌前、下颌骨增长部位的骨质量。材料和方法:本研究纳入10例骨缺损患者。在这10例骨容量不足的患者中,选择5例自体骨移植(AT)治疗,其余5例冷冻干燥皮质松质同种异体移植(AL)治疗。移植后3个月,使用3mm环钻对移植区域进行活检,并进行组织学评估。结果:组织学分析显示自体组新生骨形成区骨小梁粗大,骨腔隙含骨细胞,而同种异体移植组骨坏死,骨腔隙空。尽管AL组具有避免二次手术部位的固有优势,但与自体移植物相比,骨重塑减少。结论:10例患者均行种植。关于种植体放置期间获得的骨的性质的报告清楚地描述了移植部位的类似组织学变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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