Study of clinico-pathological characteristics of colonic polyp seen at a tertiary care hospital in East India

S. S. Giri, Amar Kumar, Sneha Singh
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Abstract

Colorectal polyps are unusual growths of epithelial tissue projecting from the mucosaof the large bowel. This study aimed to evaluate the frequency of histological pattern of polyp among colorectal polypectomy specimen concerning age, sex, size, and site and histopathological features and associated dysplasia. The study was done in the Pathology department in collaboration with the Gastroenterology Department on 115 patients. Biopsy was processed and histopathological features were studied with presence or absence of dysplasia. Most patients had constipation (40.87%) followed by rectal bleeding (40.00%) followed by pain abdomen and anemia. Male patients were 76(66.08%) followed by 39(33.91%) female patients. Among male patients most are of age range of 50-59yr (18.42%) and in females were of age range of 60-69yr. (25.64%). Grossly most polyp are of pedunculated shape (74.78%) followed by ulcerated type (13.04%) and least was of sessile appearance (12.17%). Most polyp were found in left side (descending colon: 40.87%) followed by rectum, ascending colon, sigmoid colon and transverse colon with least with caecum. Most Polyps size < 1 cm (90.40%) followed by size of polyp > 1 cm (9.60%). Regarding the histopathological evaluation of polyp we have reported tubular adenoma (53.91%) followed by hyperplastic polyp (19.13%) followed by tubulovillous adenoma (13.04%). Most of the polyp showed no dysplasia (94.64%) and dysplasia if seen both in tubular adenoma and tubulovillous adenoma. Colonoscopy is the most important tool in the detection of colonic polyp because of premalignant nature.
东印度一家三级医院结肠息肉的临床病理特征研究
结直肠息肉是一种不寻常的上皮组织增生,从大肠粘膜突出。本研究旨在评估结直肠息肉切除术标本中息肉的组织学模式的频率,包括年龄、性别、大小、部位、组织病理学特征和相关的不典型增生。这项研究是由病理学部门和消化病学部门合作完成的,研究对象是115名患者。活检处理和组织病理学特征研究是否存在不典型增生。以便秘(40.87%)居多,其次为直肠出血(40.00%),其次为腹痛和贫血。男性76例(66.08%),女性39例(33.91%)。男性患者以50 ~ 59岁居多(18.42%),女性患者以60 ~ 69岁居多。(25.64%)。息肉以带梗型最多(74.78%),溃疡型次之(13.04%),无梗型最少(12.17%)。息肉多见于左侧(降结肠占40.87%),其次为直肠、升结肠、乙状结肠和横结肠,盲肠最少。息肉大小以< 1 cm的居多(90.40%),其次为小于1 cm的(9.60%)。关于息肉的组织病理学评估,我们报道了管状腺瘤(53.91%),其次是增生性息肉(19.13%),最后是管状绒毛状腺瘤(13.04%)。绝大多数息肉未见异常增生(94.64%),管状腺瘤和管状绒毛状腺瘤均见异常增生。结肠镜检查是检测结肠息肉最重要的工具,因为它是癌前病变。
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