A Clinical Study on Hypothyroidism and Early Pregnancy Loss

J. Nath, S. Meena, T. Gupta
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Abstract

(SCH) is (>3.0 presence of normal Free T4 (0.8-2.0 ng/dL). Overt hypothyroidism (OH) has increased TSH (>3.0 mIU/L) and Free T4 (<0.8 ng/dL). Subclinical hyperthyroidism is defined as low serum TSH (<0.2 mIU/L) and normal Free T4 (0.8-2.0 ng/dL). Overt hyperthyroidism has high free T4 (>2.0 ng/dL) and low TSH (<0.2 mIU/L). This study was the aim of the of in patients presenting with early pregnancy loss. History socio-demographic parameters, parity, socio-economic status, menstrual date of her last menstrual period (LMP) were noted. Abstract Thyroid disorders are recognized associated factors for adverse pregnancy outcomes spontaneous miscarriages being an important entity. This study was conducted on 200 women who had early pregnancy losses and their thyroid profile was evaluated. Prevalence of overt and sub clinical hypothyroidism was calculated along with euthyroid women. The results obtained were statistically analysed. In conclusion, it was established that hypothyroidism, both overt and sub clinical, when untreated can lead to early pregnancy losses, therefore all antenatal women should be universally screened for thyroid dysfunction in their very first antenatal visit and treatment should be initiated at the earliest.
甲状腺功能减退与早期妊娠丢失的临床研究
(SCH) >3.0存在正常游离T4 (0.8 ~ 2.0 ng/dL)。明显的甲状腺功能减退(OH)有TSH升高(>3.0 mIU/L)和游离T4升高(2.0 ng/dL)和低TSH (<0.2 mIU/L)。这项研究的目的是在出现早期妊娠丢失的患者。记录历史、社会人口统计学参数、胎次、社会经济地位、最后一次月经日期。甲状腺疾病是公认的不良妊娠结局的相关因素,自然流产是一个重要的实体。这项研究对200名早期妊娠流产的妇女进行了研究,并对她们的甲状腺状况进行了评估。与甲状腺功能正常的妇女一起计算显性和亚临床甲状腺功能减退的患病率。对所得结果进行统计学分析。总之,甲状腺功能减退,无论是显性的还是亚临床的,如果不及时治疗,都可能导致早期妊娠丢失,因此,所有产前妇女都应该在第一次产前检查时普遍筛查甲状腺功能障碍,并尽早开始治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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