A rare presentation of acute fatty liver disease in pregnancy in the background of T-cell non-Hodgkin lymphoma

Abstract

Lymphoma is the fourth most frequently diagnosed malignancy during pregnancy after melanoma, breast cancer and cervical cancer. The commonest type of lymphoma in pregnant women is Hodgkin lymphoma with a reported incidence ranging from 1 per 1,000 to 1 per 6,000 births1. Non-Hodgkin lymphoma (NHL) in pregnancy is rare and T-cell Non-Hodgkin lymphoma (T-NHL) is a rarer form of NHL with only a few reported cases to our knowledge. NHL in pregnancy is usually diagnosed during the second or third trimester and commonly associated with aggressive histology and disseminated disease. A rapid tumour growth is thought to occur in early pregnancy, puerperium and especially during lactation and reproductive organ involvement is common2,3.