Preparation and Validation of Self-developed Bioimpedance Electrode Array for Measurement of Tumor Cells

Abstract

In Hungary, cancer causes a quarter of all deaths. Our goal is to develop a method of early diagnosis. Our research team is developing a new non-invasive bioimpedance spectrometry-based procedure that enables early detection of cancers. The measurement procedure as well as the instruments used for the measurement have been specially developed to measure tumor cells. The system, which is entirely self-developed, is an innovative solution for eliminating contact impedance due to the agility of the ions during the two electrode measurements known to this time. In our article, we present a cell culture plate that generates data that is free from the distractions of the aforementioned contact impedance. During the physical validation, we have demonstrated that the methodology we have developed can be used in a wide frequency range, so it is therefore fully suitable for further cellular testing.