Anxious-depressive Disorders in Patients with Syndrome Chronic Venous Cerebral Dysfunction and Various Levels of Blood Pressu

O. Kovalenko, N. Prityko
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The aim of the study. To conduct a comparative analysis of the interconnections of the indicators of the emotional-volitional sphere (anxiety and depression), estimated using the scales of the anxiety Ch. D. Spieberger - Yu. L. Hanin and depressions A. T. Beck, in patients with chronic cerebral venous dysfunction syndrome and without it and various indicators of arterial pressure. Materials and methods. 153 patients tested on a series of reactive and personal anxiety and depression. The main group amounted to 125 people who were elected by clinical signs of the existence of the SCVCD and various indicators of AP, and they were distributed to three clinical groups: 33 people - people with increased indicators of AP (157.20 ± 12.20 / 98.30 ± 4.20 mm Hg - hypertonics; 21 person with reduced blood pressure (100.32 ± 7.23 / 65.45 ± 6.40 mm Hg) - hypotonic; 24 people with labile AP with predominantly normal average digits of AP (125.23 ± 12.20 / 82.22 ± 4.14 mm Hg) - \"conditional\" normotonics. For comparison of indicators, 28 patients of the control group were involved - people without clinical signs of SCVCD and various indices of AP, distributed on the same principle: hypertension - eight people, hypotonics - five people, \"conditional\" normotonics - 15 people. The statistical elaboration of the results was carried out using the Medstat application package. Since the law of distribution of indicators differed from normal, for the presentation of data calculated median value and the inter-quatering interval (QI-QIII), for comparison used nonparametric criteria for U. Kruskala A. Wallis, criteria for J. Dannah and Chi-square. Results. The level of personal and reactive anxiety (among persons with chronic cerebral venous dysfunction) in hypertonics was statistically significantly higher than hypotonics. The level of depression (among persons with chronic cerebral venous dysfunction) in hypotonics was statistically significant than in hypertension and \"conditional\" normotonics. In patients in the control group, there is no statistically significant connection between the numbers of personal and reactive anxiety and the level of depression with the digits of arterial pressure. Anxiety is most often an essential part of depression. Transformation of hypotension in hypertension (and vice versa) in persons with chronic cerebral venous dysfunction syndrome may be accompanied by a transition of anxiety in depression or depression in anxiety. Conclusions. The assessment of personal and reactive anxiety on the scale of anxiety and depression revealed statistically significant bonds with arterial pressure in persons with chronic cerebral venous dysfunction syndrome. The figures of personal and reactive anxiety were statistically significant in hypertension compared to normotonics (p less than 0.001) an hypotonic (p less than 0.001). The figures of depression were statistically significant in hypotonics compared with hypertonics and normotonics (p less than 0.001). In persons from the control group, the level of reactive anxiety and blood pressure in hypertonics (p = 0.003) in comparison with hypotonic and normotonics is statistically significant. In hypеrtonics with chronic venous dysfunction syndrome, it was statistically significantly higher (p less than 0.001) level of personal anxiety compared with hypertonic control group, and among the hypotonics of the main group noted statistically significant (p less than 0.001) higher level of depression. Key words: Syndrome of chronic cerebral venous dysfunction, reactive anxiety, personal anxiety, arterial pressure, depression.","PeriodicalId":279640,"journal":{"name":"Lviv clinical bulletin","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Lviv clinical bulletin","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.25040/lkv2021.03-04.037","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract

Introduction. The syndrome of chronic venous cerebral dysfunction (SCVCD) - widely studied at present nosology. In the presence of anxiety-depressed disorders, this disease is complicated. Specific clinical manifestations of SCVCD, as pronounced practical experience, are found in people of different age and social groups, usually in conditions of comorbidity, in particular, with different arterial pressure (AP) and accompanying anxiety-depressive disorders, which is reflected in the general intellectual potential of society. In our opinion, it is an interesting and relevant issue that contributes to changes in the emotional-volitional sphere of a person carries out a SCVCD in combination with different indicators of arterial pressure (AP). The aim of the study. To conduct a comparative analysis of the interconnections of the indicators of the emotional-volitional sphere (anxiety and depression), estimated using the scales of the anxiety Ch. D. Spieberger - Yu. L. Hanin and depressions A. T. Beck, in patients with chronic cerebral venous dysfunction syndrome and without it and various indicators of arterial pressure. Materials and methods. 153 patients tested on a series of reactive and personal anxiety and depression. The main group amounted to 125 people who were elected by clinical signs of the existence of the SCVCD and various indicators of AP, and they were distributed to three clinical groups: 33 people - people with increased indicators of AP (157.20 ± 12.20 / 98.30 ± 4.20 mm Hg - hypertonics; 21 person with reduced blood pressure (100.32 ± 7.23 / 65.45 ± 6.40 mm Hg) - hypotonic; 24 people with labile AP with predominantly normal average digits of AP (125.23 ± 12.20 / 82.22 ± 4.14 mm Hg) - "conditional" normotonics. For comparison of indicators, 28 patients of the control group were involved - people without clinical signs of SCVCD and various indices of AP, distributed on the same principle: hypertension - eight people, hypotonics - five people, "conditional" normotonics - 15 people. The statistical elaboration of the results was carried out using the Medstat application package. Since the law of distribution of indicators differed from normal, for the presentation of data calculated median value and the inter-quatering interval (QI-QIII), for comparison used nonparametric criteria for U. Kruskala A. Wallis, criteria for J. Dannah and Chi-square. Results. The level of personal and reactive anxiety (among persons with chronic cerebral venous dysfunction) in hypertonics was statistically significantly higher than hypotonics. The level of depression (among persons with chronic cerebral venous dysfunction) in hypotonics was statistically significant than in hypertension and "conditional" normotonics. In patients in the control group, there is no statistically significant connection between the numbers of personal and reactive anxiety and the level of depression with the digits of arterial pressure. Anxiety is most often an essential part of depression. Transformation of hypotension in hypertension (and vice versa) in persons with chronic cerebral venous dysfunction syndrome may be accompanied by a transition of anxiety in depression or depression in anxiety. Conclusions. The assessment of personal and reactive anxiety on the scale of anxiety and depression revealed statistically significant bonds with arterial pressure in persons with chronic cerebral venous dysfunction syndrome. The figures of personal and reactive anxiety were statistically significant in hypertension compared to normotonics (p less than 0.001) an hypotonic (p less than 0.001). The figures of depression were statistically significant in hypotonics compared with hypertonics and normotonics (p less than 0.001). In persons from the control group, the level of reactive anxiety and blood pressure in hypertonics (p = 0.003) in comparison with hypotonic and normotonics is statistically significant. In hypеrtonics with chronic venous dysfunction syndrome, it was statistically significantly higher (p less than 0.001) level of personal anxiety compared with hypertonic control group, and among the hypotonics of the main group noted statistically significant (p less than 0.001) higher level of depression. Key words: Syndrome of chronic cerebral venous dysfunction, reactive anxiety, personal anxiety, arterial pressure, depression.
慢性静脉性脑功能障碍伴不同血压水平患者的焦虑抑郁障碍
介绍。慢性静脉性脑功能障碍综合征(SCVCD)是目前广泛研究的疾病之一。在存在焦虑抑郁障碍的情况下,这种疾病是复杂的。SCVCD的具体临床表现,作为明显的实践经验,存在于不同年龄和社会群体的人群中,通常以合并症的情况出现,特别是不同动脉压(AP)和伴随的焦虑抑郁障碍,这反映在社会的一般智力潜能上。在我们看来,这是一个有趣和相关的问题,有助于改变一个人的情绪-意志领域进行SCVCD与不同的动脉压(AP)指标相结合。研究的目的。对情绪-意志领域(焦虑和抑郁)指标的相互联系进行比较分析,使用焦虑量表进行估计。L. Hanin和抑郁A. T. Beck,慢性脑静脉功能障碍综合征和非慢性脑静脉功能障碍综合征患者和各种动脉压指标。材料和方法。153名患者接受了一系列反应性和个人焦虑和抑郁的测试。根据有无SCVCD的临床体征和AP各项指标选出主要组125人,分为3个临床组:AP增高组33人(157.20±12.20 / 98.30±4.20 mm Hg)高渗组;21人血压降低(100.32±7.23 / 65.45±6.40 mm Hg) -低渗;24例不稳定型AP患者,AP平均指位(125.23±12.20 / 82.22±4.14 mm Hg)主要正常-“条件”正压性。为比较指标,选取对照组28例患者,即无SCVCD临床症状和AP各项指标的患者,按相同的原则分布:高血压8人,低张力5人,“有条件”强直15人。使用Medstat应用程序包对结果进行统计细化。由于指标的分布规律不同于正态分布,对于数据计算的中位数和四分之一间隔(QI-QIII)的表示,比较使用U. Kruskala A. Wallis的非参数标准,J. Dannah的标准和卡方。结果。在慢性脑静脉功能障碍患者中,高渗血症患者的个人焦虑和反应性焦虑水平在统计学上显著高于低渗血症患者。在慢性脑静脉功能障碍患者中,低张力患者的抑郁水平比高血压和“条理性”高张力患者有统计学意义。在对照组患者中,个人焦虑和反应性焦虑的次数以及抑郁程度与动脉压数字之间没有统计学意义上的联系。焦虑通常是抑郁症的重要组成部分。慢性脑静脉功能障碍综合征患者由高血压转为低血压(反之亦然)可能伴随着抑郁转为焦虑或焦虑转为抑郁。结论。在焦虑和抑郁量表上对个人焦虑和反应性焦虑的评估显示,慢性脑静脉功能障碍综合征患者的动脉压有统计学意义。高血压患者的个人焦虑和反应性焦虑与高血压患者(p < 0.001)和高血压患者(p < 0.001)相比有统计学意义。与高张力和正张力患者相比,低张力患者抑郁的数字有统计学意义(p < 0.001)。在对照组中,与低渗和常渗患者相比,高渗患者的反应性焦虑和血压水平(p = 0.003)具有统计学意义。低渗血症合并慢性静脉功能障碍综合征患者的焦虑水平明显高于高渗对照组(p < 0.001),低渗血症主组患者抑郁水平明显高于高渗血症对照组(p < 0.001)。关键词:慢性脑静脉功能障碍综合征,反应性焦虑,个人焦虑,动脉压,抑郁
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