Laser treatment of congenital vascular birthmarks.

Pediatrician Pub Date : 1991-01-01
O T Tan, J Morelli
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引用次数: 0

Abstract

Congenital vascular birthmarks, classified as either hemangioma or vascular malformations (portwine stains), can now be cleared successfully using certain lasers. Since their introduction into medicine in the mid-1960s, several types of lasers including the argon, carbon dioxide, neodymium yttrium aluminum garnet (Nd:YAG) and pulsed tunable dye lasers have been used to treat benign cutaneous vascular lesions such as portwine stains. After extensive research examining the effects of specific laser parameters on tissue, a set of parameters was identified which together selectively destroyed blood vessels in the skin. Application of this laser technique for the treatment of benign cutaneous vascular lesions, such as portwine stains, meant that it was possible to destroy only the abnormally ectatic vessels which are inherent in these birthmarks. Because of the specificity of the laser injury, only the abnormal blood vessels are destroyed and healthy adjacent structures such as epidermal pigment and dermal collagen are left intact. Thus, unwanted adverse effects such as scar formation and pigmentary abnormalities at the laser-exposed site have been minimized. Skin treated using this combination of laser parameters normalizes in color, texture and its markings, and adnexae are maintained at the treated site. Not only has this new laser treatment provided a way of removing these disfiguring birthmarks with the return of normal-appearing skin at the treated site, but the lack of adverse effects following this treatment has meant that not only adults but children of all ages can now be treated using this technique.(ABSTRACT TRUNCATED AT 250 WORDS)

先天性血管性胎记的激光治疗。
先天性血管性胎记,归类为血管瘤或血管畸形(portwine污渍),现在可以使用某些激光成功清除。自20世纪60年代中期引入医学以来,包括氩气,二氧化碳,钕钇铝石榴石(Nd:YAG)和脉冲可调谐染料激光器在内的几种类型的激光器已被用于治疗良性皮肤血管病变,如portwine染色。在广泛研究了特定激光参数对组织的影响后,确定了一组参数,这些参数选择性地破坏了皮肤中的血管。这种激光技术应用于治疗良性皮肤血管病变,如portwine染色,意味着它可能只破坏这些胎记中固有的异常扩张的血管。由于激光损伤的特异性,只有异常血管被破坏,健康的邻近结构如表皮色素和真皮胶原蛋白完好无损。因此,不必要的副作用,如疤痕形成和色素异常的激光暴露部位已被最小化。使用这种激光参数组合治疗的皮肤在颜色、纹理和标记上正常化,附件在治疗部位保持不变。这种新的激光治疗不仅提供了一种去除这些毁容的胎记的方法,在治疗部位恢复正常的皮肤,而且这种治疗后没有副作用,这意味着不仅成年人,而且所有年龄段的儿童现在都可以使用这种技术进行治疗。(摘要删节250字)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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