Obesity and prostate cancer: the influence of metabolic syndromes

Abstract

Obesity is a significant issue for public health that is linked to a variety of chronic ailments, including cancer. Prostate cancer is the most frequent disease in men, and there is growing evidence that obesity might impact prostate cancer risk and prognosis. This article reviews the present body of scientific knowledge on the link between obesity and prostate cancer, emphasizing the involvement of metabolic syndromes. It examines the evidence indicating a direct relationship between obesity and prostate cancer risk and the likely processes behind this link, such as alterations in hormonal, immune-modulatory, and metabolic pathways. Furthermore, it investigates the influence of metabolic disorders, including insulin resistance and metabolic syndrome.