Comparing the scalogram images of the Beta-Globin gene in Homosapiens and Pan Troglodytes

Abstract

Gene sequences have enabled investigators to explore questions of genomes complexity in related organisms. The ß-globin gene is a successful example which is widely used in comparative genomics and evolutionary analyses. Herein, we report the results of a comparative DNA sequence analysis of the homologous β-globin genes in two taxa: Homosapies (human) and Pan Troglodytes (Chimpanzee). To this end, we propose a new method to represent the DNA sequences into scalogram images based on the complex Morlet wavelet transform. As for the coding method which transforms the DNA letters into a signal, we use the Frequency Chaos Game Signal of trinucleotides (coined FCGS3). The statistical analysis of the two HBB-gene images shows good correlation between the proposed method and the DNA alignment result.