Mathematical Models for Extracellular Fluid Measurement to Detect Hydration Level Based on Bioelectrical Impedance Analysis

Abstract

This paper shows mathematical models for extracellular fluid (ECF) measurements for both male and female human being based on bioelectrical impedance analysis along with prediction of hydration level. In this research total 2817 (1397 male and 1420 female) data have been used. Age, height, bioelectrical impedance at 5 kHz frequency, body mass index (BMI) are used for the development of mathematical models and the hydration level has been detected by the ratio of ECF to body weight considering standard limit. The proposed models have been analyzed statistically and the results show that the correlation (Pearson) coefficients are $0.999 (\mathrm{p}\lt 0.001)$ for both male and female individuals which denote excellent matching with actual data. Besides intervals of LOA is only -0.29 L to 0.45 L and -0.64 L to -0.06 L for male and female data respectively and most of the errors follows limit of agreement. The root mean square errors are 0.20 L for male and 0.38 L for female people. The average accuracy of proper detection of hydration level has bound 96.11%. Comparing the results of this research with existing models it is seen that the proposed models can be more suitable for ECF measurement and hydration level detection.