Management of sequelae of osteoarticular infections of infants and neonates due to delay in initiation of definitive treatment

Sayantan Makur, Arnab Karmakar, N. Das
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Abstract

Background: Osteomyelitis and septic arthritis are well-known osteoarticular infections in infants and neonates. The timely intervention of such infections is of utmost importance as delay in initiation of treatment may lead to irreversible joint damage and limb deformity also. The purpose of this study was not only to find out the sequelae of osteoarticular infections of infants and neonates due to delay in initiation of a definitive treatment but also to propose their management. Materials & Methods: This study was conducted after approval by the institutional review board. All neonates and infants with sequelae of osteoarticular infection due to delay in initiation of treatment from June 2019 to May 2021 were included in this study. Data for each patient were collected using the Hosp Gestor program. Various sequelae of osteoarticular infection were noted and then rehabilitative surgical management was done. Results: Out of 40 neonates and infants who got a delay in initiation of their treatment of osteoarticular infection, 31 (77%) came out with sequelae of osteoarticular infection. There was male predominance in this study. Sequelae were more due to osteoarticular infection of septic arthritis (53%) as compared with osteomyelitis (43%). Hip joint was found to be affected more. All patients were treated for their sequelae with rehabilitative operations. Among rehabilitative operations, hip reconstructive surgery was the most common procedure. The greater the delay in initiation of treatment in the acute stage, the more severe the sequelae. Conclusion: Early detection and institutional visit resulted in good outcomes. This study proves the truth behind the fact that delay in diagnosis and initiation of definitive treatment causes more complications and sequelae. This study also serves as a clinical guide to identify risk factors, awareness about early detection, and effective institutional treatment of osteoarticular infections in infants and neonates.
婴儿和新生儿骨关节感染的后遗症的管理,由于延迟开始明确的治疗
背景:骨髓炎和脓毒性关节炎是众所周知的婴幼儿骨关节感染。及时干预这些感染是至关重要的,因为延迟开始治疗可能导致不可逆转的关节损伤和肢体畸形。本研究的目的不仅是为了找出由于延迟开始明确治疗而导致的婴儿和新生儿骨关节感染的后遗症,而且还提出了他们的管理建议。材料与方法:本研究经机构审查委员会批准后进行。2019年6月至2021年5月期间,所有因延迟开始治疗而出现骨关节感染后遗症的新生儿和婴儿均被纳入本研究。使用Hosp Gestor程序收集每位患者的数据。观察骨关节感染的各种后遗症,并进行康复性手术治疗。结果:在40例延迟开始骨关节感染治疗的新生儿和婴儿中,31例(77%)出现骨关节感染后遗症。在这项研究中,男性占优势。脓毒性关节炎的骨关节感染(53%)比骨髓炎(43%)更容易引起后遗症。髋关节受影响更大。所有患者均行康复手术治疗其后遗症。在康复手术中,髋关节重建手术是最常见的手术。急性期开始治疗的时间越晚,后遗症越严重。结论:早期发现和到医院就诊效果良好。这项研究证明了延迟诊断和开始最终治疗会导致更多并发症和后遗症的事实背后的真相。本研究也为临床识别婴幼儿骨关节感染的危险因素、早期发现意识和有效的机构治疗提供指导。
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