[Qualitative and quantitative studies of the inflammatory reaction in the tumor boundary zone of intraoral squamous cell carcinomas].

Abstract

The inflammatory cellular infiltration in the tumor boundary zone was analyzed in 10 primary tumors, completely histologically worked up and not pretreated, using a metric and reproducible evaluation system at a line of 10 cm per case. The part of the tumor boundary zone free of inflammation varied between 2% and 79%, where as only 3 of the examined 10 tumor cases showed actions free of inflammation under 10%. In the differential cell picture of the inflammation the lymphocytes dominate (74, 12% +/- 6.79) while the part of plasmacytes varied between 1.8% and 29.2%. In spite of the exclusion of bacterially infected and necrotic tumor sections an average percentage of granulocytes (10.25% +/- 5.30) was ascertained in the inflammatory cell infiltrate.